Job Description

Are you an experienced Bioinformatics Associate with a desire to excel? If so, then Talent Software Services may have the job for you! Our client is seeking an experienced Bioinformatics Associate to work at their company in South San Francisco, CA.

Position Summary: We are seeking a highly motivated and skilled Bioinformatician to join our team. The successful candidate will play a critical role in developing, implementing, and maintaining robust bioinformatics pipelines for the analysis of next-generation sequencing (NGS) data. This position requires strong expertise in either Python or R programming for data manipulation, statistical analysis, and visualization, applied to various genomics research projects. You will work closely with molecular biologists, geneticists, and computational scientists to support our ongoing research and operations efforts.

Primary Responsibilities/Accountabilities:

• Pipeline Development: Design, develop, test, and optimize automated bioinformatics pipelines for the processing and analysis of diverse sequencing data.
• Data Analysis: Perform advanced statistical and computational analyses of genomics data, including variant calling, differential gene expression, pathway analysis, genomic annotation, and custom analyses tailored to research questions.
• Scripting & Programming: Write efficient, well-documented, and reproducible code primarily in Python or R for data cleaning, transformation, integration, and visualization.
• Algorithm Implementation: Evaluate, implement, and adapt existing bioinformatics tools and algorithms, as well as contribute to the development of Client methods.
• Collaboration: Work collaboratively with wet-lab scientists to understand experimental designs, troubleshoot data quality issues, and interpret biological findings.
• Troubleshooting & Optimization: Identify and resolve technical issues within pipelines and analyses, optimize computational efficiency, and ensure data integrity.
• Reporting & Communication: Generate comprehensive reports, visualizations, and presentations of analytical results for scientific colleagues and stakeholders. Clearly communicate complex bioinformatics concepts to non-specialists.
• Stay Current: Keep abreast of the latest advancements in bioinformatics tools, algorithms, and genomic technologies.

Qualifications:

• Experience with cloud computing platforms (e.g., AWS, GCP, Azure) and containerization (e.g., Docker, Singularity). Proficiency with workflow management systems (e.g., Snakemake, Nextflow, Cromwell/WDL).
• Experience with statistical modeling and machine learning techniques applied to biological data. Knowledge of specific sequencing applications relevant to our research (e.g., single-cell genomics, long-read sequencing, epigenomics).
• Experience working in a Linux/Unix environment.
• Familiarity with high-performance computing (HPC) clusters.

Preferred:

• Experience with cloud computing platforms (e.g., AWS, GCP, Azure) and containerization (e.g., Docker, Singularity). Proficiency with workflow management systems (e.g., Snakemake, Nextflow, Cromwell/WDL).
• Experience with statistical modeling and machine learning techniques applied to biological data. Knowledge of specific sequencing applications relevant to our research (e.g., single-cell genomics, long-read sequencing, epigenomics).
• Experience working in a Linux/Unix environment.
• Familiarity with high-performance computing (HPC) clusters.

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